Pulmonary carcinoid tumors: a single-center analysis of endocrineoncologic characteristics in Argentina
Article Sidebar
Main Article Content
Abstract
Pulmonary carcinoids (PC) show variable clinical behavior and an increasing incidence. A small proportion of PCs may be functioning. In Latin America, data on these lesions remain limited. Objective: to describe the clinical and pathological characteristics, treatment, and outcomes of patients with PC treated at a single center in Argentina, highlighting functioning tumors associated with ectopic Cushing syndrome (SCE). Materials and methods: a retrospective observational study was conducted including patients diagnosed with PC treated between 2001 and 2025 at Hospital Privado de Comunidad. Demographic variables, tumor characteristics, treatment, recurrence, and overall survival were analyzed. Results: twenty-three patients were included: 16 (70%) typical carcinoids, and 7 (30%) atypical carcinoids. Median age was 58 years, with a predominance of females (57%), and diagnosis was incidental in 39% of cases. Lymph node involvement at diagnosis was observed in 26% of PCs. All patients with tumor recurrence (14%) had positive lymph nodes at baseline. Five-year overall survival was 79.6%. Two patients (9%) presented ECS due to ACTH secretion and achieved resolution of hypercortisolism after surgery. Conclusions: this singlecenter series provides local evidence on the endocrine–oncologic characteristics of PCs in Argentina, showing their clinical heterogeneity and the occasional association with ECS.
Article Details
Section
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
EndoAr adopta una política clara y transparente respecto a los derechos de autor, alineada con los principios del acceso abierto y las buenas prácticas editoriales internacionales.
- Licencia Creative Commons CC-BY-NC (NonCommercial). Todos los artículos aceptados y publicados en la revista se distribuirán bajo la licencia Creative Commons Atribución-NoComercial 4.0 Internacional (CC-BY-NC 4.0). Esta licencia permite a cualquier persona: Compartir: copiar y redistribuir el material en cualquier medio o formato. Adaptar: remezclar, transformar y construir a partir del material. Siempre que se cumpla con las siguientes condiciones: Atribución: se debe dar crédito adecuado al autor original, proporcionar un enlace a la licencia e indicar si se realizaron cambios. No comercial: el material no puede ser usado con fines comerciales sin un acuerdo previo por escrito.
Esta política busca maximizar la difusión y el impacto de la investigación publicada, garantizando que los contenidos puedan ser utilizados y citados libremente en la comunidad científica, respetando los derechos de los autores.